Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264960 | 1.00 | ALDH1A1 (0.75) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| SCHEMBL10818750 | 0.89 | ALDH1A1 (0.62) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| SCHEMBL213849 | 0.89 | ALDH1A1 (0.62) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL10582751 | 0.86 | ALDH1A1 (0.60) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL11695961 | 0.86 | ALDH1A1 (0.60) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| SCHEMBL635165 | 0.86 | ALDH1A1 (1.00) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| SCHEMBL11793608 | 0.81 | GPR35 (0.63) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| SCHEMBL6186068 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GPR35TSHRTDP1HPGD | |
| SCHEMBL9452637 | 0.79 | ALDH1A1 (0.61) | ALDH1A1GPR35HSD17B10TSHRTDP1 | |
| SCHEMBL9859482 | 0.79 | ALDH1A1 (0.63) | ALDH1A1GPR35HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017374-A1 | A PROCESS FOR THE PREPARATION OF DIAMINORESORCINOL | THE DOW CHEMICAL COMPANY (US) | 1995-06-29 | — | — | WO | claimed |
| US-5399768-A | Process for the preparation of diaminoresorcinol | THE DOW CHEMICAL COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| CN-111116372-B | 3,4 dichloronitrobenzene full-continuous flow synthesis process under action of catalyst | 浙江本立科技股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-211921383-U | 3, 4-dichloronitrobenzene integrated full-continuous flow reaction system | 浙江本立科技股份有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-111116372-A | 3,4 dichloronitrobenzene full-continuous flow synthesis process under action of catalyst | 浙江本立科技股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| EP-1955697-B1 | 2-AMINOBENZAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) INHIBITORS USEFUL FOR THE TREATMENT OF PAIN OR BLADDER FUNCTION DISORDER | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1955697-A1 | 2-AMINOBENZAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-1995017374-A1 | A PROCESS FOR THE PREPARATION OF DIAMINORESORCINOL | THE DOW CHEMICAL COMPANY (US) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995017374-A1 | A PROCESS FOR THE PREPARATION OF DIAMINORESORCINOL | THE DOW CHEMICAL COMPANY (US) | 1995-06-29 | — | — | WO | disclosed |
| EP-0124084-B1 | PROCESS FOR THE PREPARATION OF 6-CHLORO-2,4-DINITROPHENOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |
| US-4613698-A | Process for the preparation of 6-chloro-2,4-dinitroaniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4552970-A | Solvated salts of dinitrophenylcyanamides, and a process for the preparation thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-12 | — | — | US | disclosed |
| EP-0154239-A2 | Process for the preparation of 6-chloro-2,4-nitroaniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-11 | — | — | EP | disclosed |
| US-4540832-A | Process for the preparation of 6-chloro-2,4-dinitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| EP-0124084-A2 | Process for the preparation of 6-chloro-2,4-dinitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-07 | — | — | EP | disclosed |
| EP-0053714-B1 | SOLVATED SALTS OF 2,4-DINITROPHENYL CYANAMIDES, PROCESS FOR PREPARING THEM AND THEIR APPLICATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-29 | — | — | EP | disclosed |
| EP-0053714-A1 | Solvated salts of 2,4-dinitrophenyl cyanamides, process for preparing them and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-16 | — | — | EP | disclosed |
| US-4082538-A | HERBICIDES FOR MONOCOTYLEDONS AND DICOTYLEDONS | ROHM AND HAAS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | TRPV1, TRPV2, TRPV5 | ALDH1A1 1210/4885GPR35 253/4885HSD17B10 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.