Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153612 | 0.73 | CYP19A1 (0.48) | SMN1; SMN2ALDH1A1MAPTCYP19A1RAB9A | |
| SCHEMBL27517494 | 0.68 | CA1 (0.55) | SMN1; SMN2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL26988712 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPTKMT2ACYP19A1 | |
| SCHEMBL30252315 | 0.66 | CYP19A1 (0.43) | SMN1; SMN2ALDH1A1MAPTCYP19A1RAB9A | |
| SCHEMBL1252940 | 0.66 | TSHR (0.48) | SMN1; SMN2ALDH1A1MAPTCYP19A1MAOB | |
| SCHEMBL5728797 | 0.66 | CYP19A1 (0.43) | SMN1; SMN2ALDH1A1MAPTCYP19A1RAB9A | |
| SCHEMBL11565255 | 0.66 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MAPTKMT2ACYP19A1 | |
| SCHEMBL899 | 0.66 | CYP19A1 (0.46) | SMN1; SMN2ALDH1A1MAPTCYP19A1RAB9A | |
| SCHEMBL30496165 | 0.66 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPTKMT2ACYP19A1 | |
| SCHEMBL29513232 | 0.66 | CYP19A1 (0.46) | SMN1; SMN2ALDH1A1MAPTCYP19A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |