SCHEMBL9935525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1746782	0.78	MAOB (0.40)	TDP1ALDH1A1HSD17B10CYP2A6TSHR
	SCHEMBL9739681	0.78	HTR2A (0.43)	TDP1ALDH1A1HSD17B10CYP2A6TSHR
	SCHEMBL2094693	0.78	CYP2A6 (0.35)	TDP1ALDH1A1HSD17B10CYP2A6TSHR
	SCHEMBL28268580	0.78	ALDH1A1 (0.35)	TDP1ALDH1A1HSD17B10CYP2A6TSHR
	SCHEMBL6002448	0.78	ALDH1A1 (0.35)	TDP1ALDH1A1HSD17B10CYP2A6TSHR
	SCHEMBL1613704	0.78	PTPN1 (0.36)	TDP1ALDH1A1HSD17B10CYP2A6TSHR
	SCHEMBL10370767	0.78	KDM4E (0.41)	TDP1ALDH1A1HSD17B10KDM4EMAOB
	SCHEMBL9390391	0.78	KDM4E (0.31)	TDP1ALDH1A1HSD17B10CYP2A6TSHR
	SCHEMBL1650809	0.76	KDM4E (0.50)	TDP1ALDH1A1HSD17B10KDM4EMEN1
	SCHEMBL971316	0.75	HTR2A (0.37)	ALDH1A1HSD17B10CYP2A6TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.