Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18734638 | 0.83 | RAB9A (0.50) | NPC1RAB9AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9661207 | 0.79 | ALDH1A1 (0.50) | NPC1RAB9AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL12264635 | 0.77 | ALDH1A1 (0.46) | NPC1RAB9AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL18719421 | 0.76 | ALDH1A1 (0.45) | NPC1RAB9AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL1507996 | 0.74 | KMT2A (0.54) | HPGDSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL1128796 | 0.74 | CES2 (0.59) | NPC1RAB9AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL11341286 | 0.73 | ALDH1A1 (0.45) | NPC1RAB9AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL11341283 | 0.73 | ALDH1A1 (0.45) | NPC1RAB9AHPGDTSHRSMN1; SMN2 | |
| SCHEMBL9859450 | 0.72 | MAPT (0.53) | HPGDSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9855514 | 0.72 | MAPT (0.53) | HPGDSMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430129-A2 | Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |