Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016343 | 0.86 | RAB9A (0.46) | RAB9ANPC1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL10289945 | 0.82 | RAB9A (0.42) | RAB9ANPC1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL965253 | 0.80 | P2RX7 (0.49) | RAB9ANPC1KDM4EALDH1A1KMT2A | |
| SCHEMBL269101 | 0.78 | MEN1 (0.60) | ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5337824 | 0.77 | — | — | |
| SCHEMBL145899 | 0.76 | KMT2A (0.43) | RAB9ANPC1KDM4ENPSR1ALDH1A1 | |
| SCHEMBL22103681 | 0.76 | POLB (0.64) | RAB9ANPC1KDM4EALDH1A1KMT2A | |
| SCHEMBL19151120 | 0.74 | BRD4 (0.54) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12304228 | 0.74 | TP53 (0.54) | RAB9ANPC1KDM4EALDH1A1KMT2A | |
| SCHEMBL4143510 | 0.74 | KMT2A (0.41) | RAB9ANPC1KDM4ENPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021471-A | Polyepoxides and epoxy resins modified by a pyridine compound and acid; solvent- and water-systems; coatings, molding materials and castings; chemical resistance; flexibility | THE DOW CHEMICAL COMPANY (US) | 1991-06-04 | — | — | US | claimed |