SCHEMBL9860007

SCHEMBL9860007

CCS(=O)(=O)c1nnc(N)s1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.59
CA9 Q16790 4/20 0.59
CA1 P00915 3/20 0.59
CA4 P22748 3/20 0.59
CA12 O43570 2/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA13 Q8N1Q1 1/20 0.59
CA14 Q9ULX7 1/20 0.59
CA5B Q9Y2D0 1/20 0.59
ALDH1A1 P00352 2/20 0.41
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.36
POLB P06746 1/20 0.36
F2 P00734 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11862290 0.86 CA2 (0.53) CA2CA9CA1CA4CA12
SCHEMBL10987136 0.84 CA2 (0.41) CA2CA9CA1CA4CA12
SCHEMBL11558152 0.83 CA2 (0.50) CA2CA9CA1CA4CA12
SCHEMBL11867599 0.81 CA2 (0.48) CA2CA9CA1CA4CA12
SCHEMBL11587854 0.80 ALDH1A1 (0.49) CA2CA9CA1CA4CA12
SCHEMBL9090300 0.78 CA2 (0.53) CA2CA9CA1CA4CA12
SCHEMBL6507990 0.77 CA2 (0.64) CA2CA9CA1CA4CA12
SCHEMBL3902867 0.76 CA2 (0.53) CA2CA9CA1CA4CA12
SCHEMBL9080992 0.76 CA2 (0.52) CA2CA9CA1CA4CA12
SCHEMBL28407549 0.76 CA2 (0.52) CA2CA9CA1CA4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP disclosed
US-4940705-A VIRICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-07-10 US disclosed
EP-0322643-A1 Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use BAYER AG (DE) 1989-07-05 EP disclosed
EP-0313974-A1 N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals BAYER AG (DE) 1989-05-03 EP disclosed
US-4500715-A CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES BAYER AKTIENGESELLSCHAFT (DE) 1985-02-19 US disclosed
US-4268438-A Cationic 1,3,4-thiadiazole dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed
US-4167407-A 1-Thiadiazolyl-5-acylimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1979-09-11 US disclosed
US-4111949-A HERBICIDE VELSICOL CHEMICAL COMPANY (US) 1978-09-05 US disclosed
US-4093443-A Thiadiazolylimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1978-06-06 US disclosed
US-4086238-A 1-Thiadiazolyl-4-methoxymethyl-5-hydroxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1978-04-25 US disclosed
US-4006009-A 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides VELSICOL CHEMICAL CORPORATION (US) 1977-02-01 US disclosed
US-3990882-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-11-09 US disclosed
US-3988143-A 1-Thiadiazolyl-6-alkoxytetrahydropyrimidinones VELSICOL CHEMICAL CORPORATION (US) 1976-10-26 US disclosed
US-3979388-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-09-07 US disclosed
US-3951640-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-04-20 US disclosed
US-3951976-A 1-Thiadiazoly-6-carbamoyloxytetrahydropyrimidinones VELSICOL CHEMICAL CORPORATION (US) 1976-04-20 US disclosed
US-3944409-A Method of increasing the yield of plants having storage organs by treatment with thiadiazolylimidazolines VELSICOL CHEMICAL CORPORATION (US) 1976-03-16 US disclosed
US-3933839-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-20 US disclosed
US-3932410-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-13 US disclosed
US-3931209-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-01-06 US disclosed