Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.41 |
| ▸ | CA1 | P00915 | 9/20 | 0.36 |
| ▸ | CA4 | P22748 | 7/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | CA5A | P35218 | 5/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CA11 | O75493 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860007 | 0.84 | CA2 (0.59) | CA2CA1CA4CA9CA5A | |
| SCHEMBL9736604 | 0.84 | RXFP1 (0.36) | CA2CA1CA4CA9CA5A | |
| SCHEMBL11703035 | 0.80 | CA2 (0.33) | CA2CA1CA4CA9 | |
| SCHEMBL11706188 | 0.80 | CA2 (0.37) | CA2CA1CA4CA9CA5A | |
| SCHEMBL11387456 | 0.79 | CA2 (0.36) | CA2CA1CA4CA9CA5A | |
| SCHEMBL10981850 | 0.79 | CA2 (0.51) | CA2CA1CA4CA9CA5A | |
| SCHEMBL9623867 | 0.79 | CA2 (0.43) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL11390911 | 0.79 | CA2 (0.36) | CA2CA1CA4CA9CA5A | |
| SCHEMBL11377949 | 0.77 | CA2 (0.38) | CA2CA1CA4CA9CA5A | |
| SCHEMBL11153707 | 0.77 | CA2 (0.32) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501605-A | Herbicidal heterocyclic compounds and compositions | FBC LIMITED (GB) | 1985-02-26 | — | — | US | disclosed |
| EP-0088484-A1 | Herbicidal thiadiazolyl N-aminoureas | FBC LIMITED (GB) | 1983-09-14 | — | — | EP | disclosed |