Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 9/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859724 | 0.87 | MEN1 (0.43) | MEN1KMT2APOLBHTT | |
| SCHEMBL28152912 | 0.85 | MEN1 (0.51) | MEN1KMT2APOLBKIF11HTT | |
| SCHEMBL10817073 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2APOLBKIF11HTT | |
| SCHEMBL1152521 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2APOLBKIF11HTT | |
| SCHEMBL9859794 | 0.82 | LTA4H (0.48) | MEN1KMT2APOLB | |
| SCHEMBL1152700 | 0.80 | KDM4E (0.55) | MEN1KMT2APOLBKCNH2 | |
| SCHEMBL10818771 | 0.80 | KDM4E (0.55) | MEN1KMT2APOLBKCNH2 | |
| SCHEMBL1151604 | 0.80 | ESR1 (0.42) | MEN1KMT2APOLBKIF11 | |
| SCHEMBL9099668 | 0.79 | CYP2D6 (0.49) | MEN1KMT2APOLBHTTKCNH2 | |
| SCHEMBL9859677 | 0.78 | MEN1 (0.41) | MEN1KMT2APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996225-A | Antitumor agents | FARMOS GROUP LTD. (FI) | 1991-02-26 | — | — | US | disclosed |
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |
| EP-0095875-A2 | Novel tri-phenyl alkane and alkene derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-12-07 | — | — | EP | disclosed |