Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1152521 | 1.00 | ALDH1A1 (0.42) | ALDH1A1ESR2ESR1CYP3A4MEN1 | |
| SCHEMBL1151604 | 0.97 | ESR1 (0.42) | ALDH1A1ESR2ESR1CYP3A4MEN1 | |
| SCHEMBL9859724 | 0.92 | MEN1 (0.43) | ALDH1A1CYP3A4MEN1KMT2APOLB | |
| SCHEMBL10920815 | 0.91 | ALDH1A1 (0.44) | ALDH1A1ESR2ESR1CYP3A4MEN1 | |
| SCHEMBL10916396 | 0.83 | MEN1 (0.41) | ALDH1A1ESR2ESR1CYP3A4MEN1 | |
| SCHEMBL9860176 | 0.83 | MEN1 (0.46) | MEN1KMT2APOLBKIF11HTT | |
| SCHEMBL9859794 | 0.83 | LTA4H (0.48) | MEN1KMT2APOLBLMNACYP2C19 | |
| SCHEMBL9859677 | 0.81 | MEN1 (0.41) | ALDH1A1MEN1KMT2APOLBTRPA1 | |
| SCHEMBL10800904 | 0.80 | SLC6A2 (0.41) | ALDH1A1ESR2ESR1CYP3A4MEN1 | |
| SCHEMBL28363185 | 0.78 | TRPA1 (0.42) | ALDH1A1MEN1KMT2ATRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696949-A | ANTITUMOR AGENTS, ANTIESTROGENS | FARMOS GROUP LTD. (FI) | 1987-09-29 | — | — | US | disclosed |
| EP-0095875-B1 | NOVEL TRI-PHENYL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | disclosed |