Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982954 | 0.79 | ALDH1A1 (0.41) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL6479519 | 0.79 | LMNA (0.47) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL9860880 | 0.78 | PTGDR2 (0.51) | LMNATP53CYP3A4HPGDALOX15 | |
| SCHEMBL3788910 | 0.75 | KDM4E (0.30) | ALOX15ALDH1A1 | |
| SCHEMBL15006511 | 0.72 | — | — | |
| SCHEMBL4762630 | 0.72 | TDP1 (0.42) | LMNATP53ALOX15ALDH1A1GAA | |
| SCHEMBL15132134 | 0.71 | ALDH1A1 (0.36) | LMNAALOX15ALDH1A1 | |
| SCHEMBL22140210 | 0.69 | ALDH1A1 (0.35) | LMNAALOX15ALDH1A1 | |
| SCHEMBL21692815 | 0.67 | CYP1A2 (0.35) | LMNATP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL13990327 | 0.67 | ALDH1A1 (0.33) | LMNAALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251408-B1 | NOVEL ANTI-INFLAMMATORY AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR REDUCING INFLAMMATION | THE PROCTER & GAMBLE COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0251408-A1 | Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation | THE PROCTER & GAMBLE COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |