Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861291 | 0.87 | HSD17B10 (0.71) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL29330984 | 0.83 | HPGD (0.49) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL9472028 | 0.83 | HPGD (0.67) | ALDH1A1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL6430896 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL444509 | 0.81 | HSD17B10 (0.64) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL29331006 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL25063288 | 0.79 | HSD17B10 (0.61) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL4249090 | 0.79 | HSD17B10 (0.61) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL25063269 | 0.79 | HSD17B10 (0.61) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL4246573 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HSD17B10KDM4EHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462060-A2 | Curable composition | CIBA-GEIGY AG (CH) | 1991-12-18 | — | — | EP | disclosed |