Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.63 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16272594 | 0.78 | ALOX5 (1.00) | ALOX5KDM4EMEN1KMT2APDE1A | |
| SCHEMBL5654965 | 0.76 | ALOX5 (0.64) | ALOX5PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL16319514 | 0.74 | ALOX5 (0.46) | ALOX5NQO1CASP6KDM4EMEN1 | |
| SCHEMBL8641190 | 0.72 | ALOX5 (0.53) | ALOX5MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL1420585 | 0.69 | NQO1 (0.55) | ALOX5NQO1CASP6KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL30018618 | 0.69 | MAOA (0.55) | ALOX5MAOAMAOBKDM4EMEN1 | |
| SCHEMBL38656885 | 0.69 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL9302851 | 0.69 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL14274028 | 0.68 | NQO1 (0.42) | NQO1CASP6KDM4EMEN1LMNA | |
| Anthraquinone SCHEMBL11795520 | 0.67 | BCL2 (0.54) | NQO1CASP6MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070103-A | ANTILIPEMIC AGENTS, ARTERIOSCLEROSIS | TANABE SEIYAKU CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| US-4897418-A | ANTILIPEMIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4771072-A | HYPOLIPIDEMIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0188248-A2 | Naphthalene derivatives, process for the preparation thereof and pharmaceutical composition containing same | TANABE SEIYAKU CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |