Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861353 | 0.79 | MAPK1 (0.37) | MAPK1KDM4ESMN1; SMN2EPHX2HTT | |
| SCHEMBL9721837 | 0.78 | CXCL12 (0.44) | MAPK1KDM4ESMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL9861684 | 0.74 | MAPK1 (0.50) | MAPK1SMN1; SMN2EPHX2HTTTDP1 | |
| SCHEMBL9721752 | 0.73 | TDP1 (0.47) | MAPK1KDM4ESMN1; SMN2EPHX2TDP1 | |
| SCHEMBL14593406 | 0.72 | EPHX2 (0.46) | MAPK1KDM4ESMN1; SMN2EPHX2HTT | |
| SCHEMBL19862541 | 0.72 | TDP1 (0.66) | MAPK1KDM4ESMN1; SMN2EPHX2HTT | |
| SCHEMBL9721831 | 0.72 | TDP1 (0.41) | MAPK1KDM4ESMN1; SMN2EPHX2HTT | |
| SCHEMBL6056484 | 0.71 | MAPK1 (0.43) | MAPK1KDM4ESMN1; SMN2EPHX2HTT | |
| SCHEMBL11231682 | 0.69 | LTA4H (0.55) | MAPK1EPHX2TDP1CYP1A2CYP2C19 | |
| SCHEMBL11445546 | 0.68 | CYP1A2 (0.50) | KDM4ESMN1; SMN2TDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |