Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861411 | 0.81 | S100A4 (0.36) | PDK2 | |
| SCHEMBL9861482 | 0.77 | PDK2 (0.51) | PDK2MAPTALPLPTPRCALDH1A1 | |
| SCHEMBL9861632 | 0.73 | S100A4 (0.38) | PDK2 | |
| SCHEMBL9861961 | 0.73 | KCNQ2 (0.40) | PDK2 | |
| SCHEMBL9861564 | 0.67 | ADORA2A (0.36) | PDK2MAPTPTPRCALDH1A1L3MBTL1 | |
| SCHEMBL9861333 | 0.65 | KCNQ2 (0.42) | PDK2 | |
| SCHEMBL9861915 | 0.64 | MEN1 (0.36) | PDK2MAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL18723280 | 0.60 | L3MBTL1 (0.50) | PDK2MAPTALDH1A1L3MBTL1HPGD | |
| SCHEMBL14940040 | 0.59 | CYP2D6 (0.45) | PDK2MAPTPTPRCALDH1A1L3MBTL1 | |
| SCHEMBL198911 | 0.59 | ALDH1A1 (0.60) | MAPTPTPRCALDH1A1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008425-A | Trifluoromethylation of carbonyl compounds | ETHYL CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0336371-A2 | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4845258-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| US-4844892-A | MOSQUITOES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-07-04 | — | — | US | disclosed |
| US-4804774-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4804773-A | Production of gem-disubstituted cyclohexadienones | ETHYL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4803289-A | MOSQUITOES | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1989-02-07 | — | — | US | disclosed |
| EP-0078641-B1 | IMPROVEMENTS IN OR RELATING TO PHEROMONES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-02-26 | — | — | EP | disclosed |
| EP-0078641-A1 | Improvements in or relating to pheromones | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-05-11 | — | — | EP | disclosed |
| WO-1983001621-A1 | IMPROVEMENTS IN OR RELATING TO PHEROMONES | LAURENCE, BRIAN, ROBIN | 1983-05-11 | — | — | WO | disclosed |