Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22991576 | 0.86 | CA1 (0.50) | GABRA1GABRB2CA1CA2PTGS1 | |
| SCHEMBL9812409 | 0.86 | CA1 (0.44) | GABRA1GABRB2CA1CA2PTGS1 | |
| SCHEMBL8571460 | 0.80 | ALDH1A1 (0.46) | GABRA1GABRB2CA1CA2PTGS1 | |
| SCHEMBL17281736 | 0.79 | CA1 (0.42) | GABRA1GABRB2CA1CA2PTGS1 | |
| SCHEMBL17281735 | 0.79 | CA1 (0.42) | GABRA1GABRB2CA1CA2PTGS1 | |
| SCHEMBL9812436 | 0.77 | HSD17B10 (0.46) | GABRA1GABRB2CA1CA2UGT2B7 | |
| SCHEMBL6943696 | 0.76 | GABRA1 (0.65) | GABRA1GABRB2CA1CA2PTGS1 | |
| SCHEMBL30467045 | 0.76 | GABRA1 (0.65) | GABRA1GABRB2CA1CA2PTGS1 | |
| SCHEMBL13560059 | 0.74 | UGT2B7 (0.38) | PTGS1TRPA1CACNA1CUGT2B7LMNA | |
| SCHEMBL9614164 | 0.72 | CA2 (0.44) | GABRA1GABRB2CA1CA2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032062-B2 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0032062-B1 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| US-4345054-A | High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0032062-A2 | High-molecular-weight novolak substituted phenolic resins and their preparation | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |