Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772944 | 0.91 | LMNA (0.39) | LMNATSHR | |
| SCHEMBL9859842 | 0.89 | LMNA (0.41) | LMNA | |
| SCHEMBL4179003 | 0.81 | LMNA (0.33) | LMNATSHR | |
| SCHEMBL29240698 | 0.81 | LMNA (0.53) | LMNATSHRPRKD3PRKCGPRKCB | |
| SCHEMBL28550544 | 0.81 | LMNA (0.53) | LMNATSHRPRKD3PRKCGPRKCB | |
| SCHEMBL9067103 | 0.81 | LMNA (0.53) | LMNATSHRPRKD3PRKCGPRKCB | |
| SCHEMBL5669701 | 0.79 | LMNA (0.41) | LMNA | |
| SCHEMBL5671814 | 0.79 | LMNA (0.41) | LMNA | |
| SCHEMBL113935 | 0.79 | LMNA (0.39) | LMNA | |
| SCHEMBL15032837 | 0.78 | LMNA (0.50) | LMNAPRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197540-B1 | USE OF AMINES FOR STABILIZING POLYSILOXANE FLUIDS | WACKER-CHEMIE GMBH (DE) | 1991-11-13 | — | — | EP | disclosed |
| US-4622412-A | Process for preparation of mercapto silicone fluid | GENESEE POLYMERS CORPORATION, A CORP. OF MI | 1986-11-11 | — | — | US | disclosed |
| EP-0197540-A2 | Use of amines for stabilizing polysiloxane fluids | WACKER-CHEMIE GMBH (DE) | 1986-10-15 | — | — | EP | disclosed |
| US-4612055-A | Stabilized blends of thiofunctional polysiloxane fluids and organopolysiloxane fluids and a process for stabilizing the same | SWS SILICONES CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| US-4588771-A | Stabilized thiofunctional polysiloxane fluids and a process for stabilizing the same | SWS SILICONES CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0033517-B1 | PROCESS FOR PREPARING SULFUR CONTAINING POLYSILOXANE POLYMERS, THE PRODUCTS OBTAINED THEREBY AND THE USE OF THE PRODUCTS AS CROSS-LINKING AGENTS | SWS Silicones Corporation (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4289867-A | Organofunctional polysiloxane polymers and a method for preparing the same | SWS SILICONES CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0034191-A1 | Process for preparing thiofunctional polysiloxane polymers and products obtained thereby | SWS Silicones Corporation (US) | 1981-08-26 | — | — | EP | disclosed |
| EP-0033517-A1 | Process for preparing sulfur containing polysiloxane polymers, the products obtained thereby and the use of the products as cross-linking agents | SWS Silicones Corporation (US) | 1981-08-12 | — | — | EP | disclosed |
| US-4251277-A | CORROSION INHIBITORS, RELEASE AGENTS | SWS SILICONES CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4230816-A | Thiofunctional polysiloxane polymers | SWS SILICONES CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4046795-A | Process for preparing thiofunctional polysiloxane polymers | SWS SILICONES CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |