Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720576 | 0.86 | LMNA (0.32) | LMNA | |
| SCHEMBL11772944 | 0.85 | LMNA (0.39) | LMNATSHR | |
| SCHEMBL4177999 | 0.82 | LMNA (0.36) | LMNA | |
| SCHEMBL9861548 | 0.81 | LMNA (0.41) | LMNATSHR | |
| SCHEMBL9067248 | 0.77 | LMNA (0.36) | LMNA | |
| SCHEMBL1229264 | 0.75 | CYP1A2 (0.31) | — | |
| SCHEMBL3653062 | 0.75 | — | — | |
| SCHEMBL3659454 | 0.75 | LMNA (0.48) | LMNAHSD17B10TSHR | |
| SCHEMBL31488694 | 0.75 | LMNA (0.48) | LMNAHSD17B10TSHR | |
| SCHEMBL28663849 | 0.75 | LMNA (0.48) | LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982095-B2 | Substituted organopolysiloxanes and use thereof | PHOSPHONICS LTD (GB) | 2018-05-29 | — | — | US | disclosed |
| EP-2690135-B1 | RUBBER COMPOSITION AND MANUFACTURING PROCESS THEREFOR, AND TIRE | JSR CORP (JP) | 2015-05-06 | — | — | EP | disclosed |
| EP-2690135-A1 | RUBBER COMPOSITION AND MANUFACTURING PROCESS THEREFOR, AND TIRE | JSR Corporation (JP) | 2014-01-29 | — | — | EP | disclosed |
| US-20140018479-A1 | RUBBER COMPOSITION AND MANUFACTURING PROCESS THEREFOR, AND TIRE | JSR CORPORATION (JP) | 2014-01-16 | — | — | US | disclosed |
| US-20090098082-A1 | substiuted organopolysiloxanes and use thereof | PHOSPHONICS LTD (GB) | 2009-04-16 | — | — | US | disclosed |
| EP-1786850-B1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD (GB) | 2008-11-26 | — | — | EP | disclosed |
| EP-1786850-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | Phosphonics LTD (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006013060-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD (GB) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090098082-A1 | substiuted organopolysiloxanes and use thereof | OR10J3, SOST, ITGB3 | LMNA 2360/4885ALDH1A1 1409/4885CYP3A4 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.