SCHEMBL9861563

SCHEMBL9861563

CCc1ccc(O)c(C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.50
ALDH1A1 P00352 3/20 0.38
HTT P42858 3/20 0.38
HSD17B10 Q99714 3/20 0.38
KDM4E B2RXH2 2/20 0.38
USP2 O75604 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
ALOX12 P18054 2/20 0.38
ALOX15 P16050 2/20 0.38
POLB P06746 2/20 0.37
PDK2 Q15119 1/20 0.36
PSMD14 O00487 1/20 0.35
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
BACE1 P56817 1/20 0.34
HSPA5 P11021 1/20 0.34
DAO P14920 1/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861531 0.89 TRPA1 (0.53) TRPA1ALDH1A1HTTHSD17B10KDM4E
SCHEMBL28134401 0.87 CNR1 (0.51) TRPA1HSD17B10KDM4EGAAALOX15
SCHEMBL8199656 0.82 TRPA1 (0.57) TRPA1ALDH1A1HTTHSD17B10KDM4E
SCHEMBL9861896 0.79 FFAR4 (0.42) TRPA1ALDH1A1PDK2CYP1A2CYP2A6
SCHEMBL28405891 0.76 CNR1 (0.55) TRPA1HSD17B10KDM4EGAAALOX15
SCHEMBL28402812 0.76 TRPA1 (0.50) TRPA1ALDH1A1HTTHSD17B10KDM4E
SCHEMBL245857 0.76 TRPA1 (0.59) TRPA1ALDH1A1HTTHSD17B10KDM4E
SCHEMBL13446846 0.76 TRPA1 (0.59) TRPA1ALDH1A1HTTHSD17B10KDM4E
SCHEMBL29603473 0.76 TRPA1 (0.59) TRPA1ALDH1A1HTTHSD17B10KDM4E
SCHEMBL30938647 0.74 TRPA1 (0.57) TRPA1ALDH1A1HTTHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459395-B Polycarbonate copolymer, method for producing polycarbonate copolymer, coating liquid, electrophotographic photoreceptor, and electrical device 出光兴产株式会社 2020-02-14 CN disclosed
CN-106459395-A Polycarbonate copolymer, coating liquid, electrophotographic photoreceptor, and electrical device 出光兴产株式会社 2017-02-22 CN disclosed
US-5008425-A Trifluoromethylation of carbonyl compounds ETHYL CORPORATION (US) 1991-04-16 US disclosed
EP-0336371-A2 Gem-disubstituted cyclohexadienones and their production ETHYL CORPORATION (US) 1989-10-11 EP disclosed
US-4871877-A Gem-disubstituted cyclohexadienones and their production ETHYL CORPORATION (US) 1989-10-03 US disclosed
US-4845258-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-07-04 US disclosed
US-4804774-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-02-14 US disclosed
US-4804772-A Gem-disubstituted cyclohexadienones and their production ETHYL CORPORATION (US) 1989-02-14 US disclosed
US-4804773-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-02-14 US disclosed