Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861531 | 0.85 | TRPA1 (0.53) | TRPA1POLBPDK2HSD17B10CNR1 | |
| SCHEMBL28396841 | 0.85 | CNR1 (0.58) | TRPA1PDK2HSD17B10CNR1CNR2 | |
| SCHEMBL10164822 | 0.84 | TRPA1 (0.57) | TRPA1POLBCYP19A1PDK2DAO | |
| SCHEMBL29485598 | 0.83 | CA1 (0.54) | POLBHSD17B1HSD17B2CYP19A1APP | |
| SCHEMBL14421293 | 0.83 | CA1 (0.54) | POLBHSD17B1HSD17B2CYP19A1APP | |
| SCHEMBL28402812 | 0.82 | TRPA1 (0.50) | TRPA1POLBPDK2SLC2A1HSD17B10 | |
| SCHEMBL9861563 | 0.82 | TRPA1 (0.50) | TRPA1POLBPDK2HSD17B10CNR1 | |
| SCHEMBL28646119 | 0.82 | NPC1 (0.50) | HSD17B10CNR1CNR2KDM4EALDH1A1 | |
| SCHEMBL81339 | 0.82 | KIF11 (0.49) | HSD17B1HSD17B2CYP19A1PDK2APP | |
| SCHEMBL13446846 | 0.82 | TRPA1 (0.59) | TRPA1POLBHSD17B10CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779238-B | Polycarbonate resin, method for producing polycarbonate resin, coating liquid, electrophotographic photoreceptor, and electrophotographic apparatus | 出光兴产株式会社 | 2021-10-29 | — | — | CN | claimed |
| CN-113396137-A | Method for producing 1,1, 1-trifluoro-2, 2-bisarylethane, and 1,1, 1-trifluoro-2, 2-bisarylethane | 中央硝子株式会社 | 2021-09-14 | — | — | CN | claimed |
| CN-114276531-B | Bischloroformate composition and its preparation method, polycarbonate resin and its preparation method, electrophotographic photoreceptor and electrophotographic device | 出光兴产株式会社 | 2023-10-20 | — | — | CN | disclosed |
| CN-114276531-A | Bischloroformate composition and process for producing the same, polycarbonate resin and process for producing the same, electrophotographic photoreceptor and electrophotographic apparatus | 出光兴产株式会社 | 2022-04-05 | — | — | CN | disclosed |
| CN-108779238-B | Polycarbonate resin, method for producing polycarbonate resin, coating liquid, electrophotographic photoreceptor, and electrophotographic apparatus | 出光兴产株式会社 | 2021-10-29 | — | — | CN | disclosed |
| CN-113396137-A | Method for producing 1,1, 1-trifluoro-2, 2-bisarylethane, and 1,1, 1-trifluoro-2, 2-bisarylethane | 中央硝子株式会社 | 2021-09-14 | — | — | CN | disclosed |
| CN-106459395-B | Polycarbonate copolymer, method for producing polycarbonate copolymer, coating liquid, electrophotographic photoreceptor, and electrical device | 出光兴产株式会社 | 2020-02-14 | — | — | CN | disclosed |
| EP-3505188-A1 | PRO-CYCLIC DINUCLEOTIDE CONJUGATES FOR CYTOKINE INDUCTION | Invivogen (FR) | 2019-07-03 | — | — | EP | disclosed |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2017-12-21 | — | — | US | disclosed |
| CN-106459395-A | Polycarbonate copolymer, coating liquid, electrophotographic photoreceptor, and electrical device | 出光兴产株式会社 | 2017-02-22 | — | — | CN | disclosed |
| US-20160311805-A1 | ANTI-ESTROGENIC COMPOUNDS | PFIZER INC. (US) | 2016-10-27 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20080287371-A1 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR MODULATION OF THE MIGRATING MOTOR COMPLEX | TRANZYME PHARMA INC. | 2008-11-20 | — | — | US | disclosed |
| US-20080221092-A1 | Heterobicyclic metalloprotease inhibitors | BLUHM HARALD | 2008-09-11 | — | — | US | disclosed |
| US-20080207607-A1 | Heterotricyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-08-28 | — | — | US | disclosed |
| US-20080176870-A1 | Heterobicyclic metalloprotease inhibitors | NOLTE BERT | 2008-07-24 | — | — | US | disclosed |
| WO-2008063667-A1 | HETEROTRICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| US-20080021024-A1 | Metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070155737-A1 | Heterobicyclic metalloprotease inhibitors | ALANTOS PHARMACEUTICALS, INC. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155737-A1 | Heterobicyclic metalloprotease inhibitors | ADAMTS4, ADAMTS1, ADAMTS5 | TRPA1 1954/4885POLB 3886/4885HSD17B1 3119/4885 |
| US-20080176870-A1 | Heterobicyclic metalloprotease inhibitors | ADAM17, ADAM8, ADAM10 | TRPA1 2883/4885POLB 1763/4885HSD17B1 1315/4885 |
| US-20170362210-A1 | ANTI-ESTROGENIC COMPOUNDS | ESR1, ESRRA, ESR2 | TRPA1 2845/4885POLB 4098/4885HSD17B1 126/4885 |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | TRPA1 1079/4885POLB 4713/4885HSD17B1 825/4885 |
| US-20080287371-A1 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR MODULATION OF THE MIGRATING MOTOR COMPLEX | MLNR, CCKAR, CCKBR | TRPA1 2618/4885POLB 1364/4885HSD17B1 3364/4885 |
| US-20080021024-A1 | Metalloprotease inhibitors | MMP2, MMP9, MMP3 | TRPA1 1512/4885POLB 1304/4885HSD17B1 459/4885 |
| US-20070155738-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, TIMP3, MMP3 | TRPA1 3839/4885POLB 1285/4885HSD17B1 1095/4885 |
| US-20160311805-A1 | ANTI-ESTROGENIC COMPOUNDS | ESR1, ESRRA, ESR2 | TRPA1 2845/4885POLB 4098/4885HSD17B1 126/4885 |
| US-20080221092-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, MMP3, TIMP3 | TRPA1 4021/4885POLB 1069/4885HSD17B1 1136/4885 |
| US-20080207607-A1 | Heterotricyclic metalloprotease inhibitors | MMP13, MMP3, TIMP3 | TRPA1 4001/4885POLB 1877/4885HSD17B1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.