Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104177 | 0.73 | — | — | |
| SCHEMBL3104169 | 0.73 | — | — | |
| SCHEMBL19487337 | 0.73 | — | — | |
| SCHEMBL7141244 | 0.73 | GRIK1 (0.48) | GRIK1GRIK2ALDH1A1 | |
| SCHEMBL23043980 | 0.71 | ALDH1A1 (0.40) | GRIK1GRIK2ALDH1A1 | |
| SCHEMBL6724837 | 0.71 | — | — | |
| SCHEMBL805202 | 0.71 | — | — | |
| SCHEMBL6724835 | 0.71 | — | — | |
| SCHEMBL379205 | 0.70 | GRIK1 (0.64) | GRIK1GRIK2TDP1 | |
| SCHEMBL15318070 | 0.70 | HDAC7 (0.45) | GRIK1GRIK2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251408-B1 | NOVEL ANTI-INFLAMMATORY AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR REDUCING INFLAMMATION | THE PROCTER & GAMBLE COMPANY (US) | 1991-04-17 | — | — | EP | claimed |