Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9290734 | 1.00 | NPSR1 (0.36) | NPSR1KDM4EBLMCYP2D6CYP2C19 | |
| SCHEMBL9507421 | 0.88 | — | — | |
| Sulfuric Acid SCHEMBL919865 | 0.76 | NOS3 (0.42) | NPSR1KDM4EBLMCYP2D6CYP2C19 | |
| SCHEMBL11406977 | 0.74 | — | — | |
| Sulfuric Acid SCHEMBL27931646 | 0.74 | SPHK1 (0.41) | NPSR1KDM4EBLMCYP2D6CYP2C19 | |
| Sulfuric Acid SCHEMBL3475189 | 0.72 | KDM4E (0.48) | NPSR1KDM4EBLMCYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL11409292 | 0.72 | GRIN2D (0.30) | — | |
| SCHEMBL6429906 | 0.71 | CYP2C19 (0.33) | NPSR1KDM4EBLMCYP2D6CYP2C19 | |
| Sulfuric Acid SCHEMBL10751111 | 0.67 | KDM4E (0.50) | NPSR1KDM4EBLMCYP2D6CYP2C19 | |
| SCHEMBL11071506 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983604-A | Aminoguanidine derivatives | THE ROCKEFELLER UNIVERSITY (US) | 1991-01-08 | — | — | US | disclosed |