Styrene

Styrene

SCHEMBL9861667

C=Cc1ccccc1.CCOC(C)OCC

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
TSHR P16473 1/20 0.54
LMNA P02545 1/20 0.46
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
RELA Q04206 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
PTGS2 P35354 1/20 0.36
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTR2A P28223 3/20 0.35
NR1I2 O75469 1/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL23036021 0.87 ALDH1A1 (0.41) ALDH1A1TSHRLMNAMEN1KMT2A
Styrene SCHEMBL7079576 0.86 ALDH1A1 (0.40) ALDH1A1TSHRLMNAMEN1KMT2A
Styrene SCHEMBL27623132 0.85 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ARELA
Benzaldehyde SCHEMBL19924275 0.82 ALDH1A1 (0.47) ALDH1A1TSHRLMNAMEN1KMT2A
Benzaldehyde SCHEMBL11346796 0.81 ALDH1A1 (0.50) ALDH1A1LMNAMEN1KMT2ARELA
Benzaldehyde SCHEMBL367504 0.81 ALDH1A1 (0.54) ALDH1A1LMNAMEN1KMT2ARELA
Ethylene SCHEMBL8536643 0.80 ALDH1A3 (0.42) ALDH1A1LMNAPTGS2CHRNB2CHRNB4
Styrene SCHEMBL27756934 0.79 ALDH1A1 (0.64) ALDH1A1TSHRLMNAMEN1KMT2A
Styrene SCHEMBL1732622 0.79 ALDH1A1 (0.64) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL28211071 0.79 ALDH1A1 (0.78) ALDH1A1TSHRLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0197311-B1 PROCESS FOR POLYMERIZING ETHYLENE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-12-18 EP disclosed
EP-0214127-A4 MODULAR CABLE MANAGEMENT SYSTEM FOR RELATED ELECTRONICS EQUIPMENT. HELLMAN NAT III 1989-11-07 EP disclosed
EP-0298105-A4 CONTACT LENS CLEANING COMPOSITION AND METHOD OF USE. ALCON LAB INC (US) 1989-03-29 EP disclosed
EP-0298105-A1 CONTACT LENS CLEANING COMPOSITION AND METHOD OF USE ALCON LABORATORIES, INC. (US) 1989-01-11 EP disclosed
US-4762898-A Process for polymerizing ethylene MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1988-08-09 US disclosed
WO-1988005073-A1 CONTACT LENS CLEANING COMPOSITION AND METHOD OF USE ALCON LABORATORIES, INC. (US) 1988-07-14 WO disclosed
US-4681378-A Modular cable management system for related electronics equipment MICROCOMPUTER ACCESSORIES, INC. (US) 1987-07-21 US disclosed
EP-0214127-A1 MODULAR CABLE MANAGEMENT SYSTEM FOR RELATED ELECTRONICS EQUIPMENT HELLMAN, Nat III (US) 1987-03-18 EP disclosed
EP-0197311-A2 Process for polymerizing ethylene MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-10-15 EP disclosed
WO-1986004494-A1 MODULAR CABLE MANAGEMENT SYSTEM FOR RELATED ELECTRONICS EQUIPMENT HELLMAN NAT III 1986-08-14 WO disclosed