Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857016 | 0.83 | POLB (0.38) | LMNAPOLBALDH1A1 | |
| SCHEMBL9861121 | 0.82 | IDO1 (0.49) | TAAR1IDO1DAOLMNAKMT2A | |
| SCHEMBL9861375 | 0.81 | RAB9A (0.43) | TAAR1IDO1DAOKMT2AMEN1 | |
| SCHEMBL9861031 | 0.80 | BCHE (0.44) | IDO1KMT2AALDH1A1MAPT | |
| SCHEMBL9861372 | 0.79 | RAPGEF4 (0.33) | TAAR1LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL9861108 | 0.79 | CA12 (0.46) | DAO | |
| SCHEMBL5078812 | 0.79 | CYP2C19 (0.40) | IDO1LMNAKDM4EKMT2ACYP3A4 | |
| SCHEMBL9861067 | 0.79 | SMN1; SMN2 (0.43) | LMNAKDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10709455 | 0.78 | CYP2C19 (0.39) | IDO1LMNAKDM4EKMT2ACYP3A4 | |
| SCHEMBL10708916 | 0.78 | CYP2C19 (0.39) | IDO1LMNAKDM4EKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |
| US-4581297-A | STEEL BELTED RADIAL TIRES | MONSANTO EUROPE, S.A. (BE) | 1986-04-08 | — | — | US | disclosed |
| EP-0150168-A2 | Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters | MONSANTO EUROPE S.A./N.V. (BE) | 1985-07-31 | — | — | EP | disclosed |