Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859461 | 0.86 | NPC1 (0.36) | RAPGEF4CA2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9861772 | 0.79 | TAAR1 (0.47) | NPSR1TAAR1MAPTPOLBALDH1A1 | |
| SCHEMBL10857016 | 0.79 | POLB (0.38) | POLBALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9861771 | 0.70 | IDO1 (0.43) | CA2MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9861121 | 0.70 | IDO1 (0.49) | TAAR1LMNAKMT2A | |
| SCHEMBL9861067 | 0.70 | SMN1; SMN2 (0.43) | CA2MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9861375 | 0.69 | RAB9A (0.43) | TAAR1POLBALDH1A1KMT2A | |
| SCHEMBL9861031 | 0.68 | BCHE (0.44) | CA2MAPTALDH1A1KMT2A | |
| SCHEMBL9861108 | 0.67 | CA12 (0.46) | CA2BCL2 | |
| SCHEMBL9860936 | 0.67 | TRPA1 (0.34) | CA2MAPTPOLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150168-B1 | USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS | MONSANTO EUROPE S.A./N.V. (BE) | 1991-05-08 | — | — | EP | disclosed |