Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 11/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 5/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745696 | 0.79 | ESR2 (0.55) | ESR2ACHEKDM1ACYP3A4CYP2C19 | |
| SCHEMBL10884060 | 0.79 | ESR2 (0.55) | ESR2ACHEKDM1ACYP3A4CYP2C19 | |
| SCHEMBL18559915 | 0.78 | KDM1A (0.54) | ESR2ACHEKDM1ACYP3A4DEGS1 | |
| SCHEMBL18559749 | 0.78 | KDM1A (0.54) | ESR2ACHEKDM1ACYP3A4DEGS1 | |
| SCHEMBL13609953 | 0.76 | KDM1A (0.42) | ESR2ACHEKDM1ACYP3A4ESR1 | |
| Ammonia Solution, Strong SCHEMBL268752 | 0.76 | KDM1A (0.52) | ESR2ACHEKDM1ACYP3A4DEGS1 | |
| SCHEMBL1005966 | 0.73 | ACHE (0.47) | ESR2ACHEKDM1ACYP3A4ESR1 | |
| SCHEMBL3133672 | 0.73 | ESR2 (0.62) | ESR2CYP3A4ESR1CYP2C9 | |
| SCHEMBL16000745 | 0.72 | ESR2 (0.54) | ESR2ACHEKDM1ACYP3A4ESR1 | |
| SCHEMBL21409535 | 0.71 | ESR2 (0.50) | ESR2CYP3A4ESR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414053-A2 | Polycarbonates from substituted cyclohexylidene diphenols | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |