Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357921 | 0.94 | MAPT (0.52) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL3580792 | 0.88 | NPSR1 (0.55) | SLC6A3NPSR1HMGB1CXCL12PTGS1 | |
| SCHEMBL17358226 | 0.88 | HSD17B10 (0.46) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL5852238 | 0.85 | GAA (0.49) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL17041945 | 0.82 | PTGS1 (0.41) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL8846095 | 0.81 | PTGS2 (0.57) | MAPK1NPSR1HMGB1CXCL12PTGS1 | |
| SCHEMBL2570939 | 0.81 | PTGS2 (0.57) | MAPK1NPSR1HMGB1CXCL12PTGS1 | |
| SCHEMBL27918636 | 0.80 | CYP1A2 (0.54) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL19857034 | 0.80 | HDAC3 (0.55) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL22190396 | 0.80 | MAPK1 (0.55) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103080269-B | Photochromic composition | TOKUYAMA CORP. (JP) | 2015-12-16 | — | — | CN | disclosed |
| CN-103080269-A | Photochromic composition | TOKUYAMA CORP | 2013-05-01 | — | — | CN | disclosed |
| EP-0176294-B1 | CYCLOHEXANE-1,3-DIONE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PROCESSES FOR PREPARING THEM, AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1991-06-05 | — | — | EP | disclosed |
| US-4639267-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-01-27 | — | — | US | disclosed |
| EP-0176294-A1 | Cyclohexane-1,3-dione derivatives, compositions containing them, processes for preparing them, and their use as herbicides and plant growth regulators | ICI AUSTRALIA LIMITED (AU) | 1986-04-02 | — | — | EP | disclosed |