SCHEMBL3580792

SCHEMBL3580792

Cc1cc(CCC(=O)O)cc(C)c1O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.55
THRA P10827 3/20 0.50
THRB P10828 3/20 0.50
PTGS1 P23219 2/20 0.48
PTGS2 P35354 2/20 0.48
HMGB1 P09429 1/20 0.48
CXCL12 P48061 1/20 0.48
KEAP1 Q14145 1/20 0.48
FFAR4 Q5NUL3 3/20 0.47
FFAR1 O14842 6/20 0.46
SLC6A3 Q01959 1/20 0.43
S1PR1 P21453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10990753 0.89 NPSR1 (0.46) NPSR1THRATHRBPTGS1PTGS2
SCHEMBL11241194 0.89 NPSR1 (0.46) NPSR1THRATHRBPTGS1PTGS2
SCHEMBL9861837 0.88 HDAC3 (0.52) NPSR1THRATHRBPTGS1PTGS2
SCHEMBL1206210 0.87 ACLY (0.48) NPSR1THRATHRBHMGB1CXCL12
SCHEMBL19509985 0.87 KDM4E (0.50) NPSR1THRATHRBPTGS1PTGS2
SCHEMBL8357921 0.86 MAPT (0.52) NPSR1PTGS1PTGS2HMGB1CXCL12
SCHEMBL21942034 0.85 PCNA (0.49) NPSR1THRATHRBFFAR4FFAR1
Triethylene Glycol SCHEMBL2045375 0.85 NPSR1 (0.46) NPSR1THRATHRBPTGS1PTGS2
SCHEMBL27986826 0.85 PTGS1 (0.50) THRATHRBPTGS1PTGS2HMGB1
SCHEMBL18258239 0.85 NPSR1 (0.57) NPSR1THRATHRBKEAP1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069195-B1 STABILIZED ETHYLENE/CHLOROTRIFLUOROETHYLENE COPOLYMER COMPOSITION Ausimont, U.S.A., Inc. (US) 1988-08-24 EP claimed
EP-0069195-A2 Stabilized ethylene/chlorotrifluoroethylene copolymer composition Ausimont, U.S.A., Inc. (US) 1983-01-12 EP claimed
WO-2020202210-A1 A RADIOPAQUE POLYMERIC LIQUID EMBOLIC SYSTEM SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY (IN) 2020-10-08 WO disclosed
US-20190264125-A1 LUBRICANT ADDITIVE COMPOSITION, LUBRICATING COMPOSITION CONTAINING SAME AND ENGINE OIL COMPOSITION CONSISTING OF LUBRICATING COMPOSITION ADEKA CORPORATION (JP) 2019-08-29 US disclosed
EP-2602300-B1 PHOTOCHROMIC COMPOSITION TOKUYAMA CORP (JP) 2019-06-12 EP disclosed
CN-105849206-B Adhesive composition 建筑研究和技术有限公司 2018-05-29 CN disclosed
WO-2017161144-A1 CARBONIC ANHYDRASE IX INHIBITOR CONJUGATES AND USES THEREOF ENDOCYTE, INC. (US) 2017-09-21 WO disclosed
CN-105849206-A Novel binding agent systems 建筑研究和技术有限公司 2016-08-10 CN disclosed
US-9234984-B2 Photochromic composition TOKUYAMA CORPORATION (JP) 2016-01-12 US disclosed
CN-105209446-A GPR120 agonists for the treatment of type ii diabetes JANSSEN PHARMACEUTICA NV 2015-12-30 CN disclosed
CN-103080269-B Photochromic composition TOKUYAMA CORP. (JP) 2015-12-16 CN disclosed
US-4772741-A STABILIZERS FOR POLYMERS MILLINCKRODT, INC. (US) 1988-09-20 US disclosed
EP-0069195-B1 STABILIZED ETHYLENE/CHLOROTRIFLUOROETHYLENE COPOLYMER COMPOSITION Ausimont, U.S.A., Inc. (US) 1988-08-24 EP disclosed
US-4734519-A STABILIZERS MALLINCKRODT, INC. (US) 1988-03-29 US disclosed
EP-0250087-A1 Pentaerythritol co-esters MALLINCKRODT, INC. (US) 1987-12-23 EP disclosed
EP-0219452-A1 Process for the production of sulphur-containing stabilizers with a sterically hindered phenolic group CIBA-GEIGY AG (CH) 1987-04-22 EP disclosed
US-4617404-A REACTING THIOGLYCEROL DERIVATIVE WITH A CARBOXYLIC ACID CONTAINING HINDERED PHENOL CIBA-GEIGY CORPORATION (US) 1986-10-14 US disclosed
US-4539354-A PHOSPHITE DERIVATIVE OF A PHENOL, A GROUP II METAL CARBOXYLATE ANDAN ESTER OF A POLYOL ALLIED CORPORATION (US) 1985-09-03 US disclosed
EP-0069195-A2 Stabilized ethylene/chlorotrifluoroethylene copolymer composition Ausimont, U.S.A., Inc. (US) 1983-01-12 EP disclosed
US-3969530-A 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents HOECHST AKTIENGESELLSCHAFT (DT) 1976-07-13 US disclosed