Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27325002 | 0.80 | ADORA3 (0.56) | BACE1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL8676657 | 0.80 | MAPK1 (0.60) | BACE1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL11660889 | 0.79 | ADORA3 (0.54) | BACE1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL10596845 | 0.77 | MAPK1 (0.57) | BACE1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL10434956 | 0.76 | MAPK1 (0.60) | BACE1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL11550677 | 0.76 | LTA4H (0.42) | BACE1ADORA2AKDM4EMAPTALDH1A1 | |
| SCHEMBL9862048 | 0.75 | BACE1 (0.56) | BACE1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL11894598 | 0.75 | LMNA (0.54) | ADORA3ADORA2AADORA1KDM4ELMNA | |
| SCHEMBL27559161 | 0.74 | BACE1 (0.58) | BACE1ADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL8587292 | 0.74 | MAPK1 (0.53) | BACE1ADORA3ADORA2AADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410929-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | claimed |
| EP-0410929-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |