Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635497 | 0.83 | CYP2D6 (0.37) | CYP2D6CYP1A2LMNAALDH1A1TRPA1 | |
| SCHEMBL9885327 | 0.81 | HDAC4 (0.44) | LMNAALDH1A1SMN1; SMN2POLBHDAC4 | |
| SCHEMBL11983480 | 0.80 | KDM4E (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL13395423 | 0.79 | PDE2A (0.45) | CYP2D6CYP1A2LMNAALDH1A1TRPA1 | |
| SCHEMBL19651157 | 0.77 | L3MBTL1 (0.35) | CYP2D6CYP1A2LMNAALDH1A1HIF1A | |
| SCHEMBL17424128 | 0.76 | CA1 (0.33) | CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29349873 | 0.76 | CA1 (0.41) | LMNAALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL29367415 | 0.76 | ALDH1A1 (0.39) | LMNAALDH1A1PTGS1SMN1; SMN2POLB | |
| SCHEMBL26607 | 0.76 | CA1 (0.41) | LMNAALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL1239795 | 0.76 | LMNA (0.36) | LMNAALDH1A1TRPA1PTGS1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021169-A | Heating and reacting maleic anhydride and an aliphatic olefin in the presence of a triarylphosphite; reduced levels of tar and color bodies | ETHYL CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |