SCHEMBL9862655

SCHEMBL9862655

CC1CCC(C(C)C)C(c2cc(-c3ccc(N)c(C4CC(C)CCC4C(C)C)c3)ccc2N)C1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
OPRM1 P35372 1/20 0.40
TRPM8 Q7Z2W7 3/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
TRPA1 O75762 2/20 0.38
KCNA5 P22460 1/20 0.37
LMNA P02545 1/20 0.36
EPHX1 P07099 1/20 0.36
TRPV1 Q8NER1 4/20 0.36
CNR1 P21554 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11371911 0.82 ALDH1A1 (0.44) ALDH1A1HPGDOPRM1TRPM8KDM4E
SCHEMBL9761887 0.78 OPRM1 (0.41) ALDH1A1HPGDOPRM1TRPM8KDM4E
SCHEMBL10702219 0.77 OPRM1 (0.39) ALDH1A1HPGDOPRM1TRPM8KDM4E
SCHEMBL11065428 0.77 OPRM1 (0.40) ALDH1A1HPGDOPRM1TRPM8KDM4E
SCHEMBL10700915 0.76 KCNA5 (0.50) ALDH1A1HPGDOPRM1TRPM8TRPA1
SCHEMBL13822311 0.76 OPRM1 (0.41) ALDH1A1HPGDOPRM1TRPM8KDM4E
SCHEMBL10702224 0.75 OPRM1 (0.38) ALDH1A1HPGDOPRM1TRPM8KDM4E
SCHEMBL29549463 0.74 TRPM8 (0.46) ALDH1A1HPGDOPRM1TRPM8TRPA1
SCHEMBL11065431 0.74 OPRM1 (0.39) ALDH1A1HPGDOPRM1TRPM8KDM4E
SCHEMBL31577617 0.73 OPRM1 (0.53) ALDH1A1OPRM1TRPM8TRPA1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5013799-A Flexural strength, tensile strength, nylon GILES JR HAROLD F (US) 1991-05-07 US disclosed
EP-0126781-B1 POLYETHERIMIDE-FLUORINATED POLYOLEFIN BLENDS GENERAL ELECTRIC COMPANY (US) 1987-09-09 EP disclosed
EP-0134252-B1 POLYETHERIMIDE-POLYSULFIDE BLENDS GENERAL ELECTRIC COMPANY (US) 1987-08-19 EP disclosed
US-4657987-A MOLDING MATERIALS; SHRINKAGE INHIBITION NONABSORBENT TO WATER GENERAL ELECTRIC COMPANY (US) 1987-04-14 US disclosed
EP-0091116-B1 POLYETHERIMIDE BLENDS GENERAL ELECTRIC COMPANY (US) 1986-10-15 EP disclosed
EP-0134252-A1 Polyetherimide-polysulfide blends GENERAL ELECTRIC COMPANY (US) 1985-03-20 EP disclosed
EP-0126781-A1 Polyetherimide-fluorinated polyolefin blends GENERAL ELECTRIC COMPANY (US) 1984-12-05 EP disclosed
EP-0122306-A1 Polyetherimide-acrylate copolymer blends GENERAL ELECTRIC COMPANY (US) 1984-10-24 EP disclosed
EP-0122307-A1 Blends of polyetherimide and rubber modified vinyl aromatic polymers GENERAL ELECTRIC COMPANY (US) 1984-10-24 EP disclosed
EP-0122309-A1 Polyetherimide-EPDM terpolymer blends GENERAL ELECTRIC COMPANY (US) 1984-10-24 EP disclosed
US-4427830-A PROPYLENE POLYMER GENERAL ELECTRIC COMPANY (US) 1984-01-24 US disclosed
WO-1983003417-A1 POLYETHERIMIDE-POLYSULFONE BLENDS GEN ELECTRIC (US) 1983-10-13 WO disclosed
WO-1983003416-A1 POLYETHERIMIDE BLENDS GEN ELECTRIC (US) 1983-10-13 WO disclosed
WO-1983003422-A1 POLYETHERIMED-POLYPHENYLENE ETHER BLENDS GEN ELECTRIC (US) 1983-10-13 WO disclosed
EP-0091117-A1 Polyetherimide-polysulfone blends GENERAL ELECTRIC COMPANY (US) 1983-10-12 EP disclosed
EP-0091116-A1 Polyetherimide blends GENERAL ELECTRIC COMPANY (US) 1983-10-12 EP disclosed
EP-0091118-A1 Polyetherimide-polyphenylene ether blends GENERAL ELECTRIC COMPANY (US) 1983-10-12 EP disclosed
US-4395518-A HIGH IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1983-07-26 US disclosed
US-4393168-A IMPACT AND TENSILE STRENGTH, FLEXIBILITY GENERAL ELECTRIC COMPANY (US) 1983-07-12 US disclosed
US-4390665-A IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1983-06-28 US disclosed