Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645730 | 0.88 | GSK3B (0.46) | GSK3BKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL9508765 | 0.85 | HMGB1 (0.54) | GSK3BKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL11956604 | 0.84 | GSK3B (0.54) | GSK3BKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL9631723 | 0.84 | CYP1A2 (0.50) | GSK3BKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL18629884 | 0.82 | GSK3B (0.45) | GSK3BKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL8038309 | 0.82 | KMT2A (0.53) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL6812056 | 0.80 | KMT2A (0.51) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL16233180 | 0.80 | KMT2A (0.51) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL8038602 | 0.78 | KMT2A (0.50) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL6543881 | 0.78 | GSK3B (0.59) | GSK3BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |