Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862861 | 0.88 | GSK3B (0.52) | GSK3BPTPN1KMT2AMEN1NPC1 | |
| SCHEMBL1191123 | 0.86 | TTR (0.58) | GSK3BTTRPTPN1ESR1 | |
| SCHEMBL9508765 | 0.79 | HMGB1 (0.54) | GSK3BPTPN1KMT2AMEN1NPC1 | |
| SCHEMBL28317225 | 0.79 | TTR (0.72) | TTRPTPN1ALDH1A1MAPT | |
| SCHEMBL9863598 | 0.79 | TTR (0.48) | TTRKMT2AMEN1NPC1ESR1 | |
| SCHEMBL11956604 | 0.78 | GSK3B (0.54) | GSK3BPTPN1KMT2AMEN1NPC1 | |
| SCHEMBL18629793 | 0.78 | PTPN1 (0.46) | GSK3BTTRPTPN1ESR1 | |
| SCHEMBL12187574 | 0.77 | ALOX5 (0.47) | GSK3BTTRPTPN1KMT2AMEN1 | |
| SCHEMBL9631723 | 0.77 | CYP1A2 (0.50) | GSK3BPTPN1KMT2AMEN1NPC1 | |
| SCHEMBL18629884 | 0.76 | GSK3B (0.45) | GSK3BPTPN1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131952-A1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING THIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | disclosed |