Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297712 | 1.00 | PRKCA (0.41) | PRKCATP53ELANECYP1A2GAA | |
| SCHEMBL4297713 | 1.00 | PRKCA (0.41) | PRKCATP53ELANECYP1A2GAA | |
| SCHEMBL8947297 | 0.83 | ALDH1A1 (0.39) | PRKCATP53CYP1A2GAACYP2C9 | |
| SCHEMBL15751826 | 0.79 | TP53 (0.31) | TP53ALDH1A1TSHR | |
| SCHEMBL8617231 | 0.79 | MMP1 (0.35) | PRKCATP53CYP2C19TSHRMMP1 | |
| SCHEMBL3757699 | 0.78 | PRKCA (0.44) | PRKCAELANE | |
| SCHEMBL13050301 | 0.78 | PRKCA (0.39) | PRKCAELANE | |
| SCHEMBL19812415 | 0.78 | TP53 (0.33) | TP53CYP1A2GAACYP2C9PKM | |
| SCHEMBL9862913 | 0.78 | PRKCA (0.39) | PRKCAELANE | |
| SCHEMBL7113909 | 0.78 | TP53 (0.33) | TP53CYP1A2GAACYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299484-B1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR THE SYNTHESIS OF FOSFOMYCIN | ZAMBON GROUP S.p.A. (IT) | 1991-10-09 | — | — | EP | disclosed |
| US-4937367-A | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.P.A. (IT) | 1990-06-26 | — | — | US | disclosed |
| EP-0299484-A1 | Process for the preparation of intermediates for the synthesis of fosfomycin | ZAMBON GROUP S.p.A. (IT) | 1989-01-18 | — | — | EP | disclosed |