Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862880 | 0.80 | ALDH1A1 (0.44) | ALOX15KCNH2HRH3LTA4HALOX5 | |
| SCHEMBL9668282 | 0.80 | HSD17B1 (0.41) | ESR1ESR2 | |
| SCHEMBL9668261 | 0.80 | ESR1 (0.41) | ESR1ESR2 | |
| SCHEMBL9666810 | 0.80 | ESR2 (0.44) | ESR1ESR2LSS | |
| Hydrochloric Acid SCHEMBL9705801 | 0.79 | CRHBP (0.37) | ALOX15KCNH2HRH3LTA4H | |
| SCHEMBL9863124 | 0.78 | APP (0.37) | KCNH2HRH3LTA4HALOX5LSS | |
| SCHEMBL7832996 | 0.77 | SCARB1 (0.37) | KCNH2HRH3LTA4H | |
| SCHEMBL9666112 | 0.76 | POLB (0.47) | ALOX15ALOX5 | |
| SCHEMBL10713544 | 0.76 | MAPT (0.43) | — | |
| SCHEMBL9863172 | 0.76 | HSP90AA1 (0.39) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4861791-A | Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents | STERLING DRUG INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |