Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862936 | 0.88 | ESR1 (0.39) | ESR1ESR2SMN1; SMN2HTR1DHTR1B | |
| SCHEMBL28163733 | 0.78 | HPGD (0.43) | SMN1; SMN2ADRA2AADRA1A | |
| SCHEMBL9863416 | 0.76 | CYP3A4 (0.36) | SMN1; SMN2 | |
| SCHEMBL4979332 | 0.75 | ESR1 (0.40) | ESR1ESR2SMN1; SMN2 | |
| SCHEMBL9668468 | 0.75 | ESR2 (0.47) | ESR1ESR2SMN1; SMN2ADRA2AADRA1A | |
| SCHEMBL6515577 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2ADRA2A | |
| SCHEMBL5734495 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2ADRA2A | |
| SCHEMBL31325259 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2ADRA2A | |
| SCHEMBL11192340 | 0.72 | TRPA1 (0.43) | SMN1; SMN2MMP13 | |
| SCHEMBL8853663 | 0.71 | MAOA (0.39) | ESR1ESR2SMN1; SMN2MMP13ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |