Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GART | P22102 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899064 | 0.84 | LMNA (0.45) | LMNABCHEACHEMAPTALDH1A1 | |
| SCHEMBL10898029 | 0.84 | LMNA (0.45) | LMNABCHEACHEMAPTALDH1A1 | |
| SCHEMBL8043013 | 0.84 | MAPK1 (0.41) | LMNAMAPTALDH1A1KAT2BMEN1 | |
| SCHEMBL23418074 | 0.80 | HCAR3 (0.47) | LMNABCHEACHEMAPTALDH1A1 | |
| SCHEMBL428455 | 0.73 | HCAR3 (0.53) | LMNAMAPTALDH1A1KAT2BGART | |
| SCHEMBL15239774 | 0.73 | HCAR3 (0.54) | LMNABCHEACHEMAPTALDH1A1 | |
| SCHEMBL10961239 | 0.72 | KMT2A (0.56) | MAPTALDH1A1KAT2BMEN1RAB9A | |
| SCHEMBL9428302 | 0.72 | HCAR3 (0.48) | LMNABCHEACHEMAPTALDH1A1 | |
| SCHEMBL7074757 | 0.72 | MEN1 (0.56) | LMNAMAPTALDH1A1MEN1RAB9A | |
| SCHEMBL9863059 | 0.72 | LMNA (0.62) | LMNAMAPTALDH1A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237899-B1 | PRODUCTION OF FLUOROANILINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4803270-A | Process of producing fluoroaniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0237899-A1 | Production of fluoroaniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |