Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031072 | 0.87 | POLB (0.40) | MAPK1GAARXFP1MAPTLMNA | |
| SCHEMBL9863166 | 0.84 | LMNA (0.45) | MAPTLMNAKMT2AKAT2BMEN1 | |
| SCHEMBL8090673 | 0.77 | SERPINE1 (0.55) | MAPK1GAAMAPTLMNAKMT2A | |
| SCHEMBL27499600 | 0.77 | ALDH1A1 (0.41) | MAPK1GAAMAPTLMNAKMT2A | |
| SCHEMBL8043016 | 0.77 | MAPT (0.51) | MAPK1GAAMAPTLMNASERPINE1 | |
| SCHEMBL8200499 | 0.76 | ALDH1A1 (0.55) | GAAMAPTLMNAKMT2APOLB | |
| SCHEMBL8194643 | 0.75 | MEN1 (0.42) | MAPK1LMNAKMT2AMEN1PKM | |
| SCHEMBL1192664 | 0.75 | NPSR1 (0.48) | MAPK1GAAMAPTLMNAKMT2A | |
| SCHEMBL22636966 | 0.73 | AR (0.42) | MAPK1RXFP1MAPTLMNAKMT2A | |
| SCHEMBL31510262 | 0.72 | TDP1 (0.47) | MAPK1LMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993461-A1 | NEW QUINOXALINE DIONE DERIVATIVES, THE PRODUCTION THEREOF AND USE OF THE SAME IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999000384-A1 | NEW QUINOXALINE DIONE DERIVATIVES, THE PRODUCTION THEREOF AND USE OF THE SAME IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | WO | disclosed |