Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863442 | 0.86 | PLA2G2C (0.56) | PLA2G2C | |
| Iodide SCHEMBL9693243 | 0.83 | ADRA1D (0.54) | — | |
| Hydrochloric Acid SCHEMBL9863421 | 0.82 | LPAR5 (0.43) | — | |
| Iodide SCHEMBL9863487 | 0.81 | ADRA1D (0.45) | — | |
| Hydrochloric Acid SCHEMBL9863905 | 0.81 | ADRA1D (0.54) | — | |
| Iodide SCHEMBL9863538 | 0.79 | PLA2G2C (0.56) | PLA2G2C | |
| Iodide SCHEMBL9863389 | 0.77 | PRKD3 (0.44) | — | |
| SCHEMBL8977978 | 0.76 | PLA2G2C (0.73) | PLA2G2C | |
| SCHEMBL10809548 | 0.73 | PLA2G2C (0.56) | PLA2G2C | |
| SCHEMBL10807196 | 0.73 | PLA2G2C (0.56) | PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025005-A | Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-4737518-A | ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| EP-0157609-A2 | Lipid derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-09 | — | — | EP | disclosed |