Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863510 | 0.80 | LMNA (0.52) | AOC3LMNAHRH1HTR2ATAAR1 | |
| SCHEMBL107889 | 0.77 | HRH1 (0.56) | AOC3LMNAHRH1HTR2AOPRM1 | |
| SCHEMBL8157573 | 0.75 | AOC3 (0.48) | AOC3LMNAHRH1HTR2ASIGMAR1 | |
| Hydrogen Peroxide SCHEMBL27864054 | 0.75 | HRH1 (0.54) | AOC3LMNAHRH1HTR2AOPRM1 | |
| Ammonia Solution, Strong SCHEMBL5724927 | 0.75 | HRH1 (0.54) | AOC3LMNAHRH1HTR2AOPRM1 | |
| Hydrochloric Acid SCHEMBL6521685 | 0.75 | HRH1 (0.54) | AOC3LMNAHRH1HTR2AOPRM1 | |
| SCHEMBL1263573 | 0.75 | AOC3 (0.48) | AOC3LMNAHRH1HTR2ASIGMAR1 | |
| SCHEMBL28229621 | 0.75 | HRH1 (0.54) | AOC3LMNAHRH1HTR2AOPRM1 | |
| SCHEMBL701806 | 0.74 | CA12 (0.44) | AOC3TDP1 | |
| SCHEMBL190949 | 0.73 | RIPK1 (0.59) | AOC3LMNATAAR1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025005-A | Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| EP-0369810-A2 | PAF antagonists as anti-hyperendothelinemia agents | Takeda Chemical Industries, Ltd. (JP) | 1990-05-23 | — | — | EP | disclosed |
| US-4737518-A | ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-12 | — | — | US | disclosed |