Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713981 | 0.74 | TSHR (0.39) | TSHRMAPTHTTKDM4EPPARD | |
| SCHEMBL5010543 | 0.73 | PGK1 (0.52) | TSHRMAPTHTTKDM4EPPARD | |
| SCHEMBL9863809 | 0.71 | MAPT (0.42) | TSHRMAPTHTTALDH1A1RAB9A | |
| SCHEMBL23714017 | 0.70 | TSHR (0.39) | TSHRMAPTHTTKDM4EPPARD | |
| SCHEMBL11397475 | 0.70 | MAPT (0.44) | TSHRMAPTHTTPPARDEGFR | |
| SCHEMBL992724 | 0.69 | ALDH1A1 (0.53) | KCNA5ALDH1A1NPSR1 | |
| SCHEMBL23713988 | 0.69 | TSHR (0.38) | TSHRMAPTHTTKDM4EPPARD | |
| SCHEMBL17032485 | 0.69 | KDM4E (0.51) | KDM4EALDH1A1NPSR1RAB9AMEN1 | |
| SCHEMBL31403483 | 0.69 | TLR8 (0.38) | TSHRNPY5R | |
| SCHEMBL5021640 | 0.69 | TSHR (0.34) | TSHRMAPTHTTKDM4EPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041567-A | Human and veterianary medicine; veneral diseases respiratory diseases, bovine mastitis | BEECHAM GROUP PLC (GB) | 1991-08-20 | — | — | US | disclosed |
| US-4812470-A | Antibacterial monic acid derivatives | BEECHAM GROUP P.L.C. (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0087953-B1 | ANTIBACTERIAL 1-NORMON-2-YL-HETEROCYCLIC COMPOUNDS | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |
| EP-0087953-A2 | Antibacterial 1-normon-2-yl-heterocyclic compounds | BEECHAM GROUP PLC (GB) | 1983-09-07 | — | — | EP | disclosed |