Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 15/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864381 | 0.85 | OPRK1 (0.57) | PTAFRSMN1; SMN2ALDH1A1LMNAOPRK1 | |
| SCHEMBL10469799 | 0.81 | PTAFR (0.51) | PTAFRSMN1; SMN2ALDH1A1LMNAOPRK1 | |
| SCHEMBL9864389 | 0.79 | PTAFR (0.42) | PTAFRSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL2442196 | 0.76 | GABRA1 (0.57) | PTAFRLMNAHPGDOPRK1PDE4D | |
| SCHEMBL10471631 | 0.74 | PTAFR (0.44) | PTAFRSMN1; SMN2ALDH1A1LMNAOPRK1 | |
| SCHEMBL10459976 | 0.74 | PTAFR (0.45) | PTAFR | |
| SCHEMBL10469812 | 0.74 | PTAFR (0.44) | PTAFR | |
| SCHEMBL10471633 | 0.74 | PTAFR (0.42) | PTAFRSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL10471634 | 0.73 | PTAFR (0.39) | PTAFRSMN1; SMN2ALDH1A1LMNAOPRK1 | |
| SCHEMBL10471364 | 0.73 | TUBB4A (0.51) | PTAFRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407955-A1 | New hetrazepines acting as PAF antagonists, process for their production and their use as drugs | BOEHRINGER INGELHEIM KG (DE) | 1991-01-16 | — | — | EP | disclosed |