Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865166 | 0.86 | USP7 (0.40) | USP7ALDH1A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL9876796 | 0.79 | — | — | |
| SCHEMBL9864770 | 0.79 | USP7 (0.42) | USP7SMN1; SMN2L3MBTL1KDM4ECLK1 | |
| SCHEMBL9865703 | 0.74 | ALDH1A1 (0.32) | ALDH1A1HPGD | |
| SCHEMBL9865562 | 0.70 | L3MBTL1 (0.32) | ALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL9864536 | 0.70 | ALDH1A1 (0.32) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9866108 | 0.70 | L3MBTL1 (0.34) | ALDH1A1TSHRHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL16863728 | 0.70 | USP7 (0.47) | USP7ALDH1A1TSHRPOLBSMN1; SMN2 | |
| SCHEMBL9865219 | 0.70 | — | — | |
| SCHEMBL9865076 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDSMN1; SMN2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |