Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29827386 | 0.79 | TSHR (0.46) | TSHRMMP2CHRM1COMTADRA1A | |
| SCHEMBL3289013 | 0.76 | MEN1 (0.47) | TDP2NSD2PAX8HSP90AA1HSP90AB1 | |
| SCHEMBL29535498 | 0.73 | HSP90AA1 (0.45) | TDP2NSD2PAX8HSP90AA1HSP90AB1 | |
| SCHEMBL564030 | 0.73 | CASP7 (0.50) | TSHRMMP2IDO1ALOX15KMT2A | |
| SCHEMBL1083427 | 0.73 | HSP90AA1 (0.45) | TDP2NSD2PAX8HSP90AA1HSP90AB1 | |
| SCHEMBL7718807 | 0.73 | KDM1A (0.49) | TSHRMETAP1HSP90AA1ALOX15BLM | |
| SCHEMBL3787590 | 0.72 | ALDH1A1 (0.59) | TSHRIDO1ALOX15KMT2AMEN1 | |
| SCHEMBL19463671 | 0.71 | CD44 (0.50) | TDP2NSD2PAX8ADRA1AMETAP2 | |
| SCHEMBL20600145 | 0.71 | SCN9A (0.50) | ADRA1ABLMS100A4 | |
| SCHEMBL30824252 | 0.71 | SCN9A (0.50) | ADRA1ABLMS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3151364-A | — | — | None | — | — | JP | disclosed |
| JP-H03151364-A | AMINOPYRIDINYL-AMINOPHENOL AND ITS RELATED COMPOUND | HOECHST ROUSSEL PHARMACEUT INC | 1991-06-27 | — | — | JP | disclosed |