Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789661 | 1.00 | ALDH1A1 (0.39) | ALDH1A1PLA2G1BNPSR1ATG4BMETAP2 | |
| SCHEMBL9863834 | 0.88 | ACE (0.42) | ACE | |
| SCHEMBL8568423 | 0.79 | ACE (0.45) | ALDH1A1ACE | |
| SCHEMBL10696084 | 0.79 | ACE (0.45) | ALDH1A1ACE | |
| SCHEMBL10787666 | 0.74 | ACE (0.37) | ALDH1A1PLA2G1BNPSR1ATG4BMETAP2 | |
| SCHEMBL11034466 | 0.74 | ACE (0.37) | ALDH1A1PLA2G1BNPSR1ATG4BMETAP2 | |
| SCHEMBL5806086 | 0.74 | ACE (0.45) | ACE | |
| SCHEMBL6508290 | 0.74 | ACE (0.45) | ACE | |
| SCHEMBL9731804 | 0.74 | ACE (0.45) | ACE | |
| SCHEMBL9733291 | 0.74 | ACE (0.45) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068351-A | PROCESS FOR THE PREPARATION OF N OCTAHYDROPENTA (6) PYRROLE CARBOXYLATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |
| US-5055591-A | PROCESS FOR THE PREPARATION OF OCTAHYDROPENTA(B)PYRROLE CARBOXYLATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0135181-B1 | PROCESS FOR THE PRODUCTION OF N-ALKYLATED DIPEPTIDES AND OF THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-31 | — | — | EP | disclosed |
| EP-0135182-B1 | PROCESS FOR THE PRODUCTION OF N-ALKYLATED DIPEPTIDES AND OF THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | disclosed |
| EP-0126986-B1 | PROCESS FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-05 | — | — | EP | disclosed |
| US-4525301-A | REACTING TRIFLUOROMETHANE SULFONIC ACID DERIVATIVES WITH AMINO ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-25 | — | — | US | disclosed |
| EP-0135182-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| EP-0135181-A2 | Process for the production of N-alkylated dipeptides and of their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| EP-0126986-A1 | Process for producing N-alkylated dipeptides and their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-05 | — | — | EP | disclosed |