SCHEMBL10787666

SCHEMBL10787666

CCOC(=O)[C@H](CCC1CCCCC1)N1[C@H]2CCCC[C@H]2C[C@]1(OC(=O)OCc1ccccc1)C(=O)C(C)N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 6/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 2/20 0.37
USP2 O75604 1/20 0.37
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
METAP2 P50579 1/20 0.35
REN P00797 2/20 0.34
ALDH1A1 P00352 1/20 0.34
PLA2G1B P04054 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 1/20 0.33
BCHE P06276 2/20 0.32
ACHE P22303 2/20 0.32
CACNA1F O60840 1/20 0.32
CACNA1D Q01668 1/20 0.32
CACNA1S Q13698 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11034466 1.00 ACE (0.37) ACEMEN1KMT2ALMNAUSP2
SCHEMBL10787640 0.99 ACE (0.38) ACEMEN1KMT2ALMNAUSP2
SCHEMBL6508290 0.77 ACE (0.45) ACEMEN1KMT2ALMNAUSP2
SCHEMBL5806086 0.77 ACE (0.45) ACEMEN1KMT2ALMNAUSP2
SCHEMBL9733291 0.77 ACE (0.45) ACEMEN1KMT2ALMNAUSP2
SCHEMBL9731804 0.77 ACE (0.45) ACEMEN1KMT2ALMNAUSP2
SCHEMBL9520888 0.75 ACE (0.48) ACEMEN1KMT2ALMNAUSP2
SCHEMBL5794084 0.75 ACE (0.48) ACEMEN1KMT2ALMNAUSP2
SCHEMBL9864211 0.74 ALDH1A1 (0.39) ACEMETAP2ALDH1A1PLA2G1BNPSR1
SCHEMBL10789661 0.74 ALDH1A1 (0.39) ACEMETAP2ALDH1A1PLA2G1BNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0126986-B1 PROCESS FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-05 EP disclosed