Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14492497 | 0.76 | TAAR1 (0.55) | F2RL1SMN1; SMN2CALM1TAAR1ALDH1A1 | |
| SCHEMBL13063103 | 0.76 | TAAR1 (0.55) | F2RL1SMN1; SMN2CALM1TAAR1ALDH1A1 | |
| SCHEMBL3994134 | 0.75 | F2RL1 (0.77) | F2RL1SMN1; SMN2ALOX5ALDH1A1POLB | |
| SCHEMBL28051149 | 0.74 | F2RL1 (0.74) | F2RL1SMN1; SMN2ALOX5ALDH1A1POLB | |
| SCHEMBL10370539 | 0.74 | TAAR1 (0.57) | F2RL1CALM1TAAR1ALDH1A1 | |
| SCHEMBL3943573 | 0.73 | NR1I2 (0.47) | F2RL1KMT2A | |
| SCHEMBL29326625 | 0.72 | ALOX5 (0.64) | F2RL1ALOX5CALM1ALDH1A1POLB | |
| SCHEMBL27590309 | 0.72 | SMN1; SMN2 (0.59) | F2RL1SMN1; SMN2GLAKMT2AALOX5 | |
| SCHEMBL834551 | 0.72 | TAAR1 (0.73) | F2RL1CALM1TAAR1 | |
| SCHEMBL7329940 | 0.72 | F2RL1 (0.85) | F2RL1SMN1; SMN2ALOX5CALM1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |