Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.64 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994134 | 0.89 | F2RL1 (0.77) | ALOX5F2RL1ALDH1A1POLB | |
| SCHEMBL20020280 | 0.86 | CYP1A2 (0.64) | ALOX5F2RL1 | |
| SCHEMBL28051149 | 0.84 | F2RL1 (0.74) | ALOX5F2RL1ALDH1A1POLB | |
| SCHEMBL11708838 | 0.83 | ALOX5 (0.60) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL13979616 | 0.83 | F2RL1 (0.68) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL22915010 | 0.83 | LMNA (0.58) | ALDH1A1 | |
| SCHEMBL503646 | 0.82 | ALOX5 (0.68) | ALOX5F2RL1CALM1ALDH1A1 | |
| SCHEMBL659052 | 0.82 | ALOX5 (0.68) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| SCHEMBL1105476 | 0.82 | ALOX5 (0.68) | ALOX5F2RL1CALM1ALDH1A1POLB | |
| 1,4-Dimethoxybenzene SCHEMBL27819011 | 0.82 | CNR1 (0.51) | F2RL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | PURDUE RESEARCH FOUNDATION | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238458-A1 | COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF | FAP, FIBP, FGFR1 | ALOX5 2753/4885F2RL1 20/4885CALM1 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.