Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865714 | 0.86 | ALDH1A1 (0.47) | GRIA4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9865601 | 0.83 | ALDH1A1 (0.39) | GRIA4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9864878 | 0.81 | ALDH1A1 (0.41) | GRIA4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9493186 | 0.79 | ALDH1A1 (0.38) | GRIA4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9864884 | 0.79 | GRIA4 (0.40) | GRIA4MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9864520 | 0.79 | GRIA4 (0.37) | GRIA4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9865356 | 0.74 | MEN1 (0.63) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9865456 | 0.71 | L3MBTL1 (0.55) | GRIA4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9872497 | 0.69 | BPTF (0.42) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9865072 | 0.69 | GRIA4 (0.39) | GRIA4MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |