Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | CASP1 | P29466 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064868 | 0.77 | BPTF (0.48) | BPTFALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL21122265 | 0.77 | ALDH1A1 (0.41) | BPTFALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL5040281 | 0.77 | BPTF (0.37) | BPTFALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL10288390 | 0.75 | BPTF (0.39) | BPTFALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL10308584 | 0.75 | ALDH1A1 (0.44) | BPTFALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL9493186 | 0.73 | ALDH1A1 (0.38) | BPTFALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL24488063 | 0.73 | L3MBTL1 (0.42) | BPTFALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL9864663 | 0.69 | GRIA4 (0.37) | ALDH1A1MAPTHSD17B10GAAALOX15 | |
| SCHEMBL28027611 | 0.68 | KDM4E (0.40) | ALDH1A1MAPTHSD17B10ALOX15MAPK1 | |
| SCHEMBL9872797 | 0.68 | ALDH1A1 (0.42) | BPTFALDH1A1MAPTHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064962-A | DIAMINOTHIOPHENES | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| EP-0384314-A2 | Diaminothiophenes | BASF Aktiengesellschaft (DE) | 1990-08-29 | — | — | EP | disclosed |