Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865224 | 0.80 | HDAC3 (0.41) | MEN1KMT2AMAPK1TSHRALDH1A1 | |
| SCHEMBL11566324 | 0.78 | THRB (0.40) | MEN1KMT2AMAPK1TSHRL3MBTL1 | |
| SCHEMBL9864429 | 0.78 | MEN1 (0.35) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9864434 | 0.78 | MEN1 (0.35) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL31552934 | 0.78 | DGAT1 (0.48) | MEN1KMT2AMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL8022899 | 0.76 | TSHR (0.41) | MEN1KMT2AMAPK1TSHRL3MBTL1 | |
| SCHEMBL2443924 | 0.75 | NPSR1 (0.71) | MEN1KMT2AMAPK1TSHRL3MBTL1 | |
| SCHEMBL8032317 | 0.70 | CES2 (0.48) | MEN1KMT2ATSHRL3MBTL1CYP3A4 | |
| SCHEMBL8032319 | 0.70 | CES2 (0.48) | MEN1KMT2ATSHRL3MBTL1CYP3A4 | |
| SCHEMBL8022876 | 0.69 | CES2 (0.48) | MEN1KMT2ATSHRL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |